General Information

  • ID:  hor002545
  • Uniprot ID:  A0A6I8TEZ7
  • Protein name:  NPLP-1-1
  • Gene name:  5565029
  • Organism:  Aedes aegypti (Yellowfever mosquito) (Culex aegypti)
  • Family:  NA
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Stegomyia (subgenus), Aedes (genus), Aedini (tribe), Culicinae (subfamily), Culicidae (family), Culicoidea (superfamily), Culicomorpha (infraorder), Nematocera (suborder), Diptera (order), Endopterygota (cohort), Neoptera (infraclass), Pterygota (subclass), Dicondylia, Insecta (class), Hexapoda (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  SYRSLLRDGATF
  • Length:  12
  • Propeptide:  MGNFKMLLPPKLFLRILMLLFLIVHDASSQYTDGNRRLKPCELESLLRDLTYPEEGYEMHAAALRNQLRHILEREPTDGAYQSLDEYGSYENTGPYEDKRSYRSLLRDGATFGKRNLGSLARAGLLRTPSTDYLKRSIATLAKNGQLPASREPDSEEAASAGGWNDEKRNLASARASGYMLNGKRNIASLARKYELPGKRNIQSLLRTGMLPSIAPKRNMQSLARDNSLPHFAGAAAQESKRNIQTLVRDWNLPRQQSMAADNEKRNIQSLKNAQGQGGGSSSGGRKKRELYYDDETLDDSAPEILEPVYQSSPLDYEELMEAMNEAYTPYYNSPADNHLEQKRYLGSLARAGHLHRYHRFYKRAPMGSFDGLYGNDDDDDNGTGSDNYEGEDRHKRKHASKDVLDDDNDDDDDNDEDYEPRSSVALHIPQKRHLGSIIRSGWMPSFRPSRTTGRFSRSGRARSSFTPNPSDYDNLSPAFVDDATALATAADFEQHQQQQQHPLPSAAGELPVYSPRGVLRHPELPHYTGAAFGNRPRMYAGGLPEEYLDSSSETSARPSNPFYTEDEFRCAARLRKLLYYLKKQYYLDNKYIQSVYGRNPVRY
  • Signal peptide:  NA
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  AF-A0A6I8TEZ7-F1(AlphaFold_DB_ID)
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor002545_AF2.pdbhor002545_ESM.pdb

Physical Information

Mass: 158192 Formula: C61H96N18O19
Absent amino acids: CEHIKMNPQVW Common amino acids: LRS
pI: 9.35 Basic residues: 2
Polar residues: 5 Hydrophobic residues: 4
Hydrophobicity: -35.83 Boman Index: -3250
Half-Life: 1.9 hour Half-Life Yeast: >20 hour
Half-Life E.Coli: >10 hour Aliphatic Index 73.33
Instability Index: 5095 Extinction Coefficient cystines: 1490
Absorbance 280nm: 135.45

Literature

  • PubMed ID:  20163154
  • Title:  Neuropeptidomics of the Mosquito Aedes Aegypti